The structure fire was 47 kilometres north of Christopher Lake, Sask., behind a local gas station and convenience store located on Highway 2 North and Highway 264.
A social media post from Lakeland & District Fire Department said crews arrived on the scene to a fire at the back of the main building.
Lakeland Fire said a motel behind the building is a total loss and crews “worked tirelessly” to prevent the fire from spreading to the restaurant, store, and living quarters.
There were no reported injuries and the cause of the fire is under investigation.
Lakeland Fire thanked Waskesiu Fire Department, Buckland Fire Rescue, Montreal Lake Fire Department, OSS Water hauling and SPSA Weyakwin Fire Base for their assistance.
Crews will remain on scene into Wednesday evening working on hot spots.
Global News has reached out to Lakeland & District Fire.