Police said officers spotted the vehicle in the area of 33rd Street West and Avenue P North at around 11: 15 p.m. and made a traffic stop.
The patrol officers noticed a passenger in the vehicle had brass knuckles and a knife, police said, adding he was arrested without incident.
Officers said a search of the man turned up 127.4 grams of meth and 4.4 grams of crack cocaine.
The 31-year-old Saskatoon man is facing a number of charges, including possession of meth and crack cocaine for the purpose of trafficking, possession of a dangerous weapon and breach of a weapons prohibition.
He is scheduled to appear in Saskatoon provincial court on Tuesday afternoon.