According to the Regina Police Service, the collision happened in the area of 4th Avenue and Robinson Street at about 7 p.m.
EMS transported the victim to hospital for further treatment, police say. Police confirmed that a second pedestrian, a teen boy, sustained minor injuries during the collision.
Police say traffic was diverted away from the scene as they investigated. Police requested a collision reconstruction team.
At this time, police are not releasing any more information regarding her medical condition.
Their investigation continues.
Anyone with information is asked to contact police at 306-777-6500 or Crime Stoppers at 1-800-222-8477.