Saskatoon police said 122 guns were turned into them during a province-wide amnesty program.
Guns handed over included rifles, shotguns and some prohibited weapons.
More than 500 rounds of ammunition were also turned in.
The amnesty program – launched by the Saskatchewan Association of Police Chiefs – ran from March 29 to April 27.
Police were seeking guns from owners who no longer wanted them.
A two-week campaign last year by Regina police resulted in 157 guns being turned over.
Firearm-related crime has been increasing in Saskatchewan since 2013, and the province has some of the highest rates of adult and youth accused of firearm-related offences.
-With files from The Canadian Press