The union representing about 3,000 conductors and locomotive engineers at Canadian Pacific Railway Ltd. says it has formally served the company with a 72 hour notice of an intent to strike.
The Teamsters Canada Rail Conference cites a lack of progress at the bargaining table but says talks are set to resume on Wednesday.
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The union says should the two sides fail to reach a negotiated settlement, the workers will walk out at 12:01 a.m. on Saturday, April 21.
Canadian Pacific workers voted 94.2 per cent on April 6 in favour of strike action to support their contract demands.
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The previous contract expired at the end of 2017 and federal mediators were brought in on Jan. 29, 2018.
The Teamsters reached a tentative deal with Canadian National Railway Co. last month for a new contract for about 1,700 CN locomotive engineers in Canada. Voting on that tentative deal is underway.