Deerfoot Trail was temporarily closed to northbound traffic on Tuesday morning following a crash that badly injured one person.
Calgary police said the single-vehicle collision happened on northbound Deerfoot Trail just before 5 a.m.
According to police, the vehicle rolled and caught fire underneath the Seton Boulevard overpass.
Paramedics rushed the 40-year-old man driving the vehicle to hospital in serious condition.
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Police said the driver was the only person in the vehicle at the time of the crash.
Northbound Deerfoot Trail reopened shortly before 9 a.m.