Toronto police say a 23-year-old man was shot while driving his car in Etobicoke on Tuesday.
Police said the shooting happened on southbound Highway 427 at Eva Road shortly before 2 a.m.
Investigators said the injured man managed to leave the area and made a phone call to 911 that he was shot while inside his vehicle.
He was then located a short distance away at North Queen Street and The Queensway and taken to hospital with serious injuries, police said.
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Police could not confirm if anyone else was inside the vehicle.
Investigators said they do not have a suspect description.