Shelton, 43, confirmed the upcoming appearance in a Twitter post on Tuesday evening, hinting that the duo would play a rendition of their latest collaboration, Nobody But You.
The Voice co-stars began dating in September 2015 after working together on the popular singing competition TV series. Stefani, 50, joined the show as a full-time coach for its seventh season the year prior.
The duet comes from the country star’s latest compilation, Fully Loaded: God’s Country (2019).
Though Stefani did not release any new music in 2019, Shelton put out a handful of singles, including Nobody But You.
His smash-hit radio anthem God’s Country earned a nomination for Best Country Solo Performance at this year’s awards show.
American rock legends Aerosmith will also take the stage on “music’s biggest night” to perform a medley of some of their biggest hits.
Nobody But You and Fully Loaded: God’s Country are now available through all major streaming platforms.
You can catch the upcoming performance live on Sunday, Jan. 26 at 8 p.m. ET.