The bust happened just before noon on Monday when members of the Prince Albert integrated street enforcement team searched an apartment in the 400-block of 12 Street East.
Police said they seized suspected meth packaged in four baggies that weighed just under 73 grams, 52 hydromorophone pills, a water bottled believed to be half-full of GHB, a large sum of cash, a digital scale, a cellphone and tablet, and bear spray.
A home in the 700-block of McCraney Crescent, which police said the accused frequents, was also searched. A Taser flashlight and a digital scale were seized.
The 39-year-old Prince Albert man is facing a number of charges including possession of meth, hydromorphone and gamma hydroxybutonic for the purpose of trafficking, and possession of bear spray and a Taser flashlight for a purpose dangerous to the public peace.
He is scheduled to appear Tuesday in Prince Albert provincial court.