One person is in a trauma centre with serious injuries after an SUV collided with a pickup truck near Guelph.
The crash happened on Highway 6 just south of Fergus early Wednesday morning.
Wellington County OPP along with emergency services arrived at around 8 a.m.
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Investigators say the driver of the pickup was initially transported to a local hospital before being airlifted to a trauma centre.
The driver of the SUV walked away unhurt.
The road was closed as investigators looked into the cause of the crash.
They are asking any witnesses to contact Wellington County OPP.