A serious crash on the QEII Highway south of Edmonton near Maskwacis sent two people to hospital with serious injuries and led to the southbound lanes being closed Wednesday afternoon.
The crash between the semi-tractor trailer and a car happened just before 1 p.m., just south of Highway 611.
RCMP said two people in the car were seriously injured.
STARS Air Ambulance said a crew from Edmonton was dispatched just after 1 p.m., and airlifted a 32-year-old man with traumatic injuries to the University of Alberta Hospital. He was stable upon arrival in Edmonton, STARS said.
RCMP said another passenger of the car was taken to an area hospital by ground EMS.
The collision remains under investigation, however Ponoka RCMP said road conditions are believed a contributing factor. It was snowing in the area at the time of the crash.
Southbound traffic on Highway 2 was being diverted around the collision scene and as of 4 p.m., the detour was expected to continue for several hours.
Motorists were asked to avoid the area and to plan an alternate route.