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China says WHO supported early use of coronavirus vaccine candidate outside of trials

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The World Health Organization supported China’s campaign to vaccinate certain people against coronavirus in July while clinical trials were still under way, a Chinese health official said on Friday, although some experts have expressed concern about the move.

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China launched its emergency programme in July, having communicated with the WHO in late June, according to Zheng Zhongwei, a National Health Commission official.

Hundreds of thousands essential workers and other limited groups of people considered at high risk of infection have been given the vaccine, even though its efficacy and safety had not been fully established as Phase 3 clinical trials were incomplete, raising concerns among experts.

“At end-June, China’s State Council approved a plan of COVID-19 vaccine emergency use program,” Zheng told a news conference.

“After the approval, on June 29, we made a communication with the relevant representatives of the WHO Office in China, and obtained support and understanding from WHO,” Zheng said.

Countries have autonomy to issue emergency use authorization for any health product according to the national regulations and legislations, Dr. Mariangela Simão, assistant director-general at the WHO, said on Friday at a news conference in Geneva.

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WHO chief scientist Soumya Swaminathan said earlier this month that emergency use authorization for coronavirus vaccine is a “temporary solution,” and that the long-term solution lay in completion of Phase 3 trials.

Beijing has not publicly released full details of its emergency use programme.

At least three vaccine candidates, including two developed by state-backed China National Biotec Group (CNBG) and one from Sinovac Biotech, all in Phase 3 trials overseas, are included in the emergency use programme.

A fourth experimental vaccine developed by CanSino Biologics were approved to be used in the Chinese military in June.

China’s annual production capacity of COVID-19 vaccines is expected to reach 610 million doses by end-2020 and 1 billion doses by 2021, Zheng said.

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In China, the vaccine price will be affordable for the general public, Zheng added.

(Reporting by Gabriel Crossley and Roxanne Liu in Beijing; Editing by Ryan Woo and Simon Cameron-Moore)

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