Emergency crews say they are at the scene where a vehicle struck a home on Grey Street.
The London Fire Department says the gas line has been severed and crews are evacuating the area on Grey Street from Colborne to Waterloo streets.
Officials say the driver was not trapped.
London Fire is currently working with Enbridge Gas, London police, and the Middlesex London Paramedic Service.
The Grey Street incident comes one year after a vehicle struck a home on Woodman Avenue, severing a gas line and sparking an explosion that damaged multiple homes in the area.