A portion of Anthony Henday Drive was closed to traffic late Thursday morning after a fiery two-vehicle collision on the eastern side of the ring road.
RCMP said the crash happened at around 11:15 a.m. in the southbound lanes of Highway 216 near the Sherwood Park Freeway exit.
RCMP Const. Chantelle Kelly said the collision involved a pickup truck and a semi truck.
RCMP said the investigation has found the pickup truck was reversing on the right shoulder of the highway when it struck the passenger side of the semi-tractor-trailer carrying diesel fuel. The semi caught fire, crossed the southbound lanes of the highway and stopped in the centre median.
Video from the collision site showed heavy black smoke coming from the front of the semi.
The drivers of both vehicles were taken to hospital with non-life-threatening injuries.
Shortly before noon, Kelly said traffic in both directions along the Henday was being rerouted. Southbound traffic was being rerouted at Baseline Road, while those heading north were detoured onto Wye Road.
One lane in each direction along the Henday reopened Thursday afternoon, but traffic delays persisted through the evening rush hour.
The highway reopened later Thursday evening.