Officials said both southbound lanes are open to traffic with no restrictions.
READ MORE: CN train derails north of Saskatoon
One northbound lane is open, with speed and traffic restrictions still in place.
All 30 cars from a CN train that derailed Tuesday morning north of Saskatoon have been cleared from the crash scene.
WATCH BELOW: Coverage of the train derailment north of Saskatoon
The cars left the track on Highway 11, closing all lanes to traffic.
Investigators from the Transportation Safety Board (TSB) continue to investigate the cause of the derailment.
READ MORE: CP freight train derails near Ernfold, Sask.