Hamilton Police have made six arrests and laid 48 charges with the help of counterparts in Niagara and Peel as part of a special drug investigation called Project Purple Rain.
In conducting four raids, officers seized about $250,000 worth of fentanyl, cocaine, and methamphetamine.
Along with the arrests, officers seized four handguns and 150 rounds of ammunition as well as $20,000 in cash.
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No time frame was released for the raids.
Police say this investigation is on-going.