Blazers forward Orrin Centazzo scored the game’s first two goals, giving them a 2-0 lead heading into the second period.
Pats defencemen Nikita Sedov cut the lead to 2-1 with his third of the season 14 minutes into the second.
Just three minutes later, Logan Stankoven restored the Blazers two-goal lead and were up 3-1 heading into the final frame.
Ryan Hughes scored an empty netter late in the third giving the Blazers a 4-1 lead.
Caiden Daley got one back with his first goal of the season and first as a Pat, after being traded to Regina in late October.
Pats goalie Max Paddock stopped 43-of-46 shots he faced while Blazers netminder Dylan Garand stopped 21-of-23.
The Pats are back at it on Friday when they host the Kelowna Rockets (17-9-1-2). Game time is 7 p.m.