Toronto emergency teams launched a full water rescue response mission after a vehicle crashed through ice and sunk into the Keating Channel Saturday morning.
Police say they received a call for a collision at 8:45 a.m. in the area of Lake Shore Boulevard East and Cherry Street.
Investigators say an 18-year-old man was driving a Jeep and lost control, striking a Ford being driven by a 32-year-old man.
The Jeep exited the roadway as a result and broke through the ice on the Don River.
No one was seen exiting the vehicle when it entered the water.
Toronto Fire Capt. Deepak Chagger confirmed the 18-year-old driver was still inside when the vehicle crashed into the water.
After hours of searching, a man police say they believe to be the driver was recovered from the icy water.
He was transported to hospital in critical condition, where he later succumbed to his injuries and died, medics said.
The driver of the other vehicle was also taken to hospital, police said.
Road closures were in effect in the area to accommodate the water response vehicles.
An investigation by members of Traffic Services has now opened.