Emergency crews were called to the area of Jane Street and Yorkwoods Gate, south of Finch Avenue West, at 10:30 p.m.
Toronto paramedics say the victim had serious injuries and was rushed to a trauma centre.
“Our investigation is underway, and what we believe happened is four young men were crossing the street and they were approached by a vehicle,” Insp. Jim Gotell told reporters Thursday night.
“One of the suspects in the vehicle opened fire on the four young men, and one of the males was shot.”
Gotell said the boy’s injuries are serious but not life-threatening. He said none of the others were injured in the gunfire.
Police had originally said the victim was a 15-year-old boy but in an update Thursday morning police said the boy is 16-years-old.
Cody Lam told Global News the shooting victim came to his door.
“He got shot twice. One went through his foot and one went through his chin,” Lam said, adding he helped treat the victim until emergency crews arrived.
“I was really scared,” he said.
Police are asking anyone with information related to the shooting or dashcam footage of the area to contact investigators at 416-808-3100.
The shooting came shortly after three other reported instances of gunfire in Toronto.
Police say a 64-year-old man was taken to a hospital in serious condition after being shot during one of the incidents.
As of Thursday night, it wasn’t clear if all of the incidents were connected.