Two youths were taken to hospital with serious injuries after they were hit by a vehicle on Parkhill Road West.
The collision happened just after 5 p.m., near the Ravenwood Drive intersection.
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A teenaged girl was taken to Peterborough Regional Health Centre (PRHC) and then airlifted by Ornge to a Toronto hospital with serious injuries.
The other pedestrian was taken to PRHC with leg injuries.
Parkhill was closed for about 7 hours for an investigation.
Police are looking for witnesses.