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WHO declares highly-infectious Marburg virus outbreak in Ghana

Marburg virus, cut-away illustration. This tubular RNA (ribonucleic acid) virus causes Marburg haemorrhagic fever in humans and non-human primates. Symptoms of the disease include fever, muscle pain, rash, diarrhoea and haemorrhage. The virus was first documented in 1967 in laboratories in Marburg and Frankfurt in Germany, and in Belgrade in Yugoslavia. Getty Images

The World Health Organization has declared Ghana‘s first outbreak of the Ebola-like Marburg virus disease after labs confirmed the infections in two cases announced earlier this month.

The disease, a very infectious hemorrhagic fever in the same family as Ebola, is spread to people by fruit bats and transmitted among people through direct contact with bodily fluids of infected people and surfaces, WHO said.

A preliminary analysis of samples from two patients from Ghana’s southern Ashanti region – both of whom died and were unrelated – turned up positive, but were forwarded for full confirmation to the Institute Pasteur in Dakar, Senegal. That U.N. health agency lab corroborated the results from the Noguchi Memorial Institute for Medical Research in Ghana, WHO said in a statement Sunday.

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The first case was a 26-year-old male who checked into a hospital on June 26 and died on June 27. The second was a 51 -year-old male who went to the hospital on June 28 and died the same day, WHO said, adding that both men sought treatment at the same hospital.

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“Health authorities have responded swiftly, getting a head start preparing for a possible outbreak,” said WHO Regional Director for Africa Dr. Matshidiso Moeti. “This is good because without immediate and decisive action, Marburg can easily get out of hand. WHO is on the ground supporting health authorities and now that the outbreak is declared, we are marshalling more resources for the response.”

More than 90 contacts, including health workers and community members, have been identified and are being monitored, WHO said.

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Marburg is potentially very harmful and deadly: Case fatality rates in past outbreaks have ranged from 24% to 88%.

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This outbreak marks only the second time that the disease has been detected in West Africa – after Guinea confirmed a single case detected in August, according to WHO. The outbreak in Guinea was declared over five weeks later.

Previous Marburg outbreaks and individual cases have appeared in Angola, Congo, Kenya, South Africa and Uganda, WHO said.

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