Hamilton Police are investigating a serious collision on the Red Hill Valley Parkway (RHVP).
Police believe it happened shortly after 5:30 p.m. on Saturday in the southbound lanes near Queenston Road, where about four vehicles were involved in the crash.
Hamilton Police Collision Reconstruction Unit investigators say a Ford pick-up truck travelling northbound in the far right lane on the RHVP at the King Street on-ramp made contact with the east shoulder and the driver lost control.
The truck slid across the northbound lanes, through the grass median colliding head-on with a GMC van travelling southbound in the passing lane.
Two people were taken to hospital, with the driver of the GMC suffering serious but non-life-threatening injuries. The 43-year-old Toronto man is currently in hospital in stable condition.
The southbound lanes of the Red Hill were closed for the investigation Saturday evening, leading to a massive traffic backlog in the area.
No charges have been laid in the incident.
Police are asking witnesses of the crash to contact the Division 10 Traffic Office by calling 905-546-4756 or anonymously call Crime Stoppers at 1-800-222-8477 (TIPS).