White Butte RCMP say a “serious two vehicle collision” shut down both westbound lanes of Highway 1 east of Regina for several hours.
The crash between two semis happened early just before 4:30 a.m. CT Thursday near White City.
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Four people were taken to hospital with minor injuries.
Police said westbound traffic between Balgonie and White City and traffic was being detoured.
One lane has been opened to traffic and police said the full scene is not expected to be cleared until early afternoon.
Drivers are being asked to avoid the area if at all possible and exercise caution around emergency personnel.
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