A fire broke out a multi-unit home in 1100 block of Wascana Street in Regina early Saturday morning.
The Regina Fire Department said crews received a call shortly after 3 a.m., and police blocked off several intersections in the area.
Fire crews said the fire is under investigation and there were no injuries.
The fire department said that people from 22 units were displaced from multiple buildings due to fire, smoke and water damage.
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