The Sea-to-Sky Highway was closed to northbound traffic near Lions Bay for several hours after a potential hit-and-run on Tuesday.
Officials were able to reopen the route to one lane by 4 p.m. and announced that the route had been cleared shortly before 8 p.m.
BC Emergency Health Services said it was notified of the crash just before 11:20 a.m. of a crash involving a motorcycle.
Two ambulances were deployed, but no one was transported to hospital.
Squamish RCMP said the Integrated Collision Analysis and Reconstruction Team had been deployed.
Investigators also asked the public to be on the lookout for a white Honda with rear-end damage and missing part of its rear bumper.
“If seen, please call Police and do not approach,” police said.
Injuries from the collision were not immediately clear.