The national weather agency says 10 cm of snow is possible for Tuesday, and that motorists should be prepared for changing road conditions.
The snow is expected to taper off to a few flurries by evening.
Areas under the special weather statement include the Shuswap plus West and East Columbia regions.
Yoho Park/Kootenay Park is under a snowfall warning, where 15 cm is expected.
For the latest highway conditions throughout the province, visit DriveBC.