Traffic is closed at The Parkway and Sir Sandford Fleming Drive intersection following a multi-vehicle collision on Monday morning.
Two men in one delivery truck were taken to hospital after the vehicle collided with another larger commercial truck around 11 a.m. The area also has access ramps to Highway 115.
The cab of the commercial truck ended up in the back of the delivery truck.
The daily email you need for
Peterborough's top news stories.
There were at least three other vehicles at the scene which sustained damage. The drivers and passengers were not injured.
Peterborough Police Service were advising motorists to avoid the area.
The cause of the collision remains under investigation.
The intersection reopened around 2:10 p.m.
WATCH: Peterborough’s worst intersections for collisions