MD Ambulance said one man was killed after a collision between a car and a semi on Highway 41 between Saskatoon and Aberdeen.
Saskatoon RCMP said the crash happened at around 7 a.m. CT on Saturday when the vehicles collided in the northbound lanes near Aberdeen.
The driver of the car, a 68-year-old man from Melfort, was declared dead at the scene by paramedics. His name has not been released.
The driver of the semi was not injured.
Saskatoon RCMP and a collision reconstructionist continue to investigate.
Aberdeen is approximately 35 kilometres northeast of Saskatoon.