Highway 401 was closed in both directions between Highway 33 and County Road 40 in Trenton on Wednesday morning following a collision.
Quinte West OPP tweeted out the notice to drivers just after 5 a.m.
Photos shared with Global News by the Quinte West Fire Department show a tractor-trailer that had collided with another vehicle.
Police held the scene for several hours while detours were in place.
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No injuries were reported.
A 58-year-old man from Downsview has been charged with careless driving.
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