A 35-year-old man was killed on Avenue X North on Saturday morning.
Police said officers and paramedics responded to calls of gunfire in the 200 block of Avenue X North at 7:20 a.m. Saturday.
They discovered an injured man, who was taken to hospital where he later died.
The major crimes, forensic identification and target enforcement units are investigating, the police said in a statement.
Long-time residents in the area told Global News the violence has been getting worse over the last five years.
Another resident said police officers knocking on doors has become a common occurrence in the area.
Police are asking anyone with information to contact them at 306-975-8300 or Crime Stoppers at 1-800-222-8477.