Wellington OPP say a 24-year-old woman was killed in a crash near Drayton on Monday afternoon.
Emergency crews responded to the single-vehicle collision north of the town on Wellington Road 8 at around 1:30 p.m.
Police said initial reports indicated that a vehicle went into a ditch.
The driver, who was the lone occupant of the vehicle, was pronounced dead at the scene.
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Police have identified her as Jordan Marie MacDougall of Moorefield.
Wellington Road 8 was closed between Sideroad 12 and Sideroad 15 for the investigation, and drivers were asked to avoid the area.
The cause of the collision is still under investigation.
Drayton is about 45 kilometres northwest of Guelph.