A truck carrying fertilizer rolled over on Monday evening in the City of Kawartha Lakes near Pontypool.
Emergency crews were called to the scene on Boundary Road at Highway 35 around 6:30 p.m.
Crews worked to contain a diesel spill and clean up fertilizer from the roadway.
City of Kawartha Lakes OPP are investigating the cause of the crash.
The exact amount of fertilizer spilled is unclear.
The westbound lane of Boundary Road and a section of the southbound lane of Highway 35 was blocked by police and cleanup crews.