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Success of kidney transplant is dependent on age and sex: study

WATCH ABOVE: A new study out of the McGill University Health Centre looks at how age and gender can affect the outcomes for kidney transplant patients. As Global’s Felicia Parrillo reports, the study could lead to new personalized treatments for patients – Jun 8, 2017

It’s been a long road for 22-year-old Sarah-Anne Heroux-Blanchard.

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When she was just 9 years old, doctors discovered she has a rare disease that affects her kidney function, and so at the age of 14, she underwent a transplant.

“When you’re young, you just don’t understand everything,” she said. “[For example], you don’t understand your medication, if you don’t take it, you can lose your kidney.”

Heroux-Blanchard’s transplant was successful, but it didn’t completely cure her.

WATCH BELOW: Kidney transplant surgery livestreamed to raise awareness about kidney disease, organ donation

Her disease is still attacking her kidneys, so she’s back in hospital for treatment.

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Pediatric Nephrologist Dr. Bethany Foster, said transplants may not work so well in other young women.

Foster was recently involved in a study that compared kidney transplant survival rates in males and females.

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The study, conducted by the Research Institute of the McGill University Health Centre (RI-MUHC) and the University of Montreal Hospital Research Center (CRCHUM), showed that females between the ages of 15 and 24 have a 30 to 40 per cent higher risk of kidney graft failure than males in the same age group.

READ MORE: MUHC first in North America to use new augmented reality surgery technology

The same study however, also revealed that women over the age of 45 had a slightly better graft survival than males, of the same age.

“Once we observed all of these things, we had to try and figure out what could possibly explain this,” said Foster. “And one of the most obvious things that may explain this is hormonal differences.”

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According to Foster, who is also a part of The Canadian National Transplant Research Program, the results of the study suggest that health professionals may need to start thinking about treating girls and boys and men and women differently.

“Many drugs are developed and tested on men only, or have been in the past,” Foster said. “And the assumption is that they’re going to work the same in women, as they do in men, and that is not the case.”

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