The man ran away from an approaching patrol officer, dropping the knife as he did so, police say.
Read more: Saskatoon Police arrest man with fake gun
An officer chased the suspect into a backyard in the 100 block of Avenue U South, where the suspect turned and sprayed the officer with bear spray.
The suspect escaped and a canine unit couldn’t find him.
Medavie Health Services West paramedics treated the officer, who has now returned to duty.
Police are asking anyone with information to contact them, at 306-975-8300, or Crime Stoppers at 1-800-222-8477.
The police statement described the wanted man as approximately five feet 10 inches tall, 180 pounds, between the ages of 25 and 30. He was last seen wearing a black baseball hat, a white shirt and black shorts.